(2R,3S,5R)-5-(6-Amino-8-(methylamino)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol CAS 13389-10-1

Purity 97%+In StockPharmaceutical Standards
CAS No.13389-10-1
Molecular FormulaC27H25F3N6O
Molecular Weight506.52 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2R,3S,5R)-5-(6-Amino-8-(methylamino)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol CAS 13389-10-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 506.52 g/mol gives (2R,3S,5R)-5-(6-Amino-8-(methylamino)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(2R,3S,5R)-5-(6-Amino-8-(methylamino)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 13389-10-1), molecular formula C27H25F3N6O and molecular weight 506.52 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (2R,3S,5R)-5-(6-Amino-8-(methylamino)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (C27H25F3N6O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (2R,3S,5R)-5-(6-Amino-8-(methylamino)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC27H25F3N6O
Molecular Weight506.52 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)17.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1960
Halogen ContentF-containing
Nitrogen Atoms6

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