5-Bromo-8-fluoro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione CAS 1339384-06-3
| CAS No. | 1339384-06-3 |
| Molecular Formula | C8H3BrFNO3 |
| Molecular Weight | 260.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Bromo-8-fluoro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-Bromo-8-fluoro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione (CAS 1339384-06-3), molecular formula C8H3BrFNO3 and molecular weight 260.02 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromo-8-fluoro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione (C8H3BrFNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H3BrFNO3 |
| Molecular Weight | 260.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 6-Bromo-8-fluoro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione (CAS 1049118-00-4)
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Recommended Standards
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