7-Chloro-4,4-dimethyl-3,4-dihydroquinolin-2(1H)-one CAS 133999-06-1
| CAS No. | 133999-06-1 |
| Molecular Formula | C11H12ClNO |
| Molecular Weight | 209.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 7-Chloro-4,4-dimethyl-3,4-dihydroquinolin-2(1H)-one (CAS 133999-06-1), a certified reference material (molecular formula C11H12ClNO, MW 209.67 g/mol) for analytical method development and quality control.
The molecular framework of 7-Chloro-4,4-dimethyl-3,4-dihydroquinolin-2(1H)-one (C11H12ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Chloro-4,4-dimethyl-3,4-dihydroquinolin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12ClNO |
| Molecular Weight | 209.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 3-(4-Chlorophenyl)piperidin-2-one (CAS 1267774-08-2)
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- Galanin Message Associated Peptide (1-41) amide trifluoroacetate salt (CAS 132699-74-2)
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