t-butyl-dimethyl­silyl-(3-propionyl­phenol­) CAS 134154-50-0

Purity 97%+In StockPharmaceutical Standards
CAS No.134154-50-0
Molecular FormulaC15H24O2Si
Molecular Weight264.44 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

t-butyl-dimethyl­silyl-(3-propionyl­phenol­) CAS 134154-50-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 264.44 g/mol gives t-butyl-dimethyl­silyl-(3-propionyl­phenol­) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

t-butyl-dimethyl­silyl-(3-propionyl­phenol­) (CAS 134154-50-0) is a high-purity analytical reference standard with the molecular formula C15H24O2Si and a molecular weight of 264.44 g/mol.

The molecular framework of t-butyl-dimethyl­silyl-(3-propionyl­phenol­) (C15H24O2Si) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H24O2Si
Molecular Weight264.44 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at room temperature
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995

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