7-Bromo-5-fluoro-3,4-dihydroisoquinolin-1(2H)-one CAS 1341674-79-0
| CAS No. | 1341674-79-0 |
| Molecular Formula | C9H7BrFNO |
| Molecular Weight | 244.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 7-Bromo-5-fluoro-3,4-dihydroisoquinolin-1(2H)-one (C9H7BrFNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 7-Bromo-5-fluoro-3,4-dihydroisoquinolin-1(2H)-one (CAS 1341674-79-0), a certified reference material (molecular formula C9H7BrFNO, MW 244.06 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H7BrFNO |
| Molecular Weight | 244.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 3-(3-Bromo-4-fluorophenyl)-3-hydroxypropanenitrile (CAS 1075178-76-5)
- N-(2-bromo-4-fluorophenyl)acrylamide (CAS 1094231-21-6)
- 3-(4-Bromo-2-fluorophenoxy)propanenitrile (CAS 1152534-02-5)
- N-(5-bromo-2-fluorophenyl)acrylamide (CAS 1156153-35-3)
- 6-Bromo-7-fluoro-3,4-dihydroquinolin-2(1H)-one (CAS 1156389-00-2)
- (7-Bromo-4-fluoro-1H-indol-3-yl)methanol (CAS 1158471-53-4)
- 6-Bromo-8-fluoro-3,4-dihydroquinolin-2(1H)-one, 97% (CAS 1194459-25-0)
- 6-Bromo-8-fluoro-3,4-dihydroisoquinolin-1(2H)-one (CAS 1242157-15-8)
Recommended Standards
- 4-(5-Bromo-2-fluorophenyl)azetidin-2-one (CAS 1340065-84-0)
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- 4-(4-Bromo-2-fluorophenyl)azetidin-2-one (CAS 1339218-02-8)
- (4-Bromo-7-fluoro-1H-indol-3-yl)methanol (CAS 1360946-31-1)
- 1-Benzyl-1H-benzo[d]imidazol-2(3H)-one (CAS 28643-53-0)
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- 3-(2-Bromophenoxy)-7-hydroxy-4H-chromen-4-one (CAS 196928-47-9)
- 6-Oxo-1,6-dihydropyridazine-3-carbaldehyde hydrate (CAS 1409932-24-6)
- 2-Bromo-6-(chloromethyl)-5-(difluoromethyl)-3-methylpyridine (CAS 1804850-63-2)
- (2S,4S)-4-Fluoro-2-methylpyrrolidine hydrochloride (CAS 2828444-34-2)
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