1-(1-(2,2-Difluoroethyl)-1H-pyrazol-4-yl)ethan-1-amine CAS 1341764-65-5
| CAS No. | 1341764-65-5 |
| Molecular Formula | C7H11F2N3 |
| Molecular Weight | 175.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(1-(2,2-Difluoroethyl)-1H-pyrazol-4-yl)ethan-1-amine (CAS 1341764-65-5) is a high-purity analytical reference standard with the molecular formula C7H11F2N3 and a molecular weight of 175.18 g/mol.
The molecular framework of 1-(1-(2,2-Difluoroethyl)-1H-pyrazol-4-yl)ethan-1-amine (C7H11F2N3) is characterized by a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(1-(2,2-Difluoroethyl)-1H-pyrazol-4-yl)ethan-1-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H11F2N3 |
| Molecular Weight | 175.18 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluoroethyl Standards
- 1-(2,2-Difluoroethyl)-3,5-dimethyl-1h-pyrazol-4-amine (CAS 1006348-51-1)
- 2-(1-(2,2-Difluoroethyl)-1H-pyrazol-4-yl)ethan-1-amine (CAS 1340574-31-3)
- 1-(1-(2,2-Difluoroethyl)-1H-pyrazol-4-yl)-N-methylmethanamine (CAS 1343036-98-5)
- 1-(1-(2,2-Difluoroethyl)-1h-pyrazol-3-yl)-N-methylmethanamine (CAS 1345510-70-4)
- 1-(1-(2,2-Difluoroethyl)-1h-pyrazol-5-yl)-N-methylmethanamine (CAS 1345510-71-5)
- 1-(1-(2,2-Difluoroethyl)-1H-imidazol-2-yl)-N-methylmethanamine (CAS 1554179-46-2)
- N-(2,2-difluoroethyl)-2-fluoroaniline (CAS 1178171-38-4)
- n-(2,2-Difluoroethyl)-4-fluoroaniline (CAS 1178500-33-8)
Recommended Standards
- (R)-2-amino-4-methoxy-3,3-dimethyl-4-oxobutanoic acid (CAS 1336574-07-2)
- 2-Formamido-5-methoxypentanoic acid (CAS 1343504-22-2)
- (S)-2-amino-4-methoxy-3,3-dimethyl-4-oxobutanoic acid (CAS 1336122-69-0)
- 2-Formamido-4-methoxy-3-methylbutanoic acid (CAS 1343971-44-7)
- Z-D-Arg(NO2)-OH (CAS 2279-08-5)
- 5-Bromo-6-chlorobenzo[d]isoxazol-3-ol (CAS 855996-71-3)
- 5-Bromo-2-fluorothioanisole (CAS 1370025-62-9)
- 2-(Pyridin-4-yl)acetaldehyde (CAS 878499-08-2)
- 1-(1-(2-Fluoroethyl)-1H-pyrazol-5-yl)-N-(furan-2-ylmethyl)methanamine hydrochloride (CAS 1856071-90-3)
- tert-Butyl {[1-(cyclohexylmethyl)piperidin-4-yl]methyl}carbamate (CAS 1286274-44-9)
- 3-(4-Amino-3,5-dimethyl-1h-pyrazol-1-yl)propanamide (CAS 1152559-08-4)
- 2-Chlorobenzyl alcohol (CAS 17849-38-6)
- 5-(Morpholine-4-carbonyl)-1h-pyrazol-3-amine (CAS 1346943-94-9)
- Insulin Degludec Impurity 3 (CAS CATO-C4X-21573)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com