4-Chloro-5-iodo-2,6-dimethoxypyrimidine CAS 134221-53-7
| CAS No. | 134221-53-7 |
| Molecular Formula | C6H6ClIN2O2 |
| Molecular Weight | 300.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-5-iodo-2,6-dimethoxypyrimidine (CAS 134221-53-7) is a high-purity analytical reference standard with the molecular formula C6H6ClIN2O2 and a molecular weight of 300.48 g/mol.
Based on its molecular formula C6H6ClIN2O2, 4-Chloro-5-iodo-2,6-dimethoxypyrimidine contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/iodine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 300.48 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-5-iodo-2,6-dimethoxypyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H6ClIN2O2 |
| Molecular Weight | 300.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- Ethyl 5-chloro-4-iodo-1H-pyrazole-3-carboxylate (CAS 1934360-92-5)
- 1-(6-Chloro-2-fluoro-3-iodophenyl)ethanol (CAS 2635937-66-3)
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- 3-Chloro-2-fluoro-5-iodobenzoic acid (CAS 1000162-09-3)
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Recommended Standards
- 11-Hydroxyoctadecanoic acid (CAS 13419-91-5)
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- rac-3-Hydroxyoctadecanoic Acid (CAS 17773-30-7)
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- 6-Chloropyridine-2,4-diamine (CAS 1206248-43-2)
- (S)-methyl 2-(5-(((R)-2-amino-3-mercaptopropyl)amino)-[1,1'-biphenyl]-2-ylcarboxamido)-4-(methylthio)butanoate hydrochloride (CAS 180977-34-8)
- Benzyl 4-Iodobenzoate (CAS 136618-42-3)
- 6-methylpyridazine-4-carbaldehyde (CAS 1083401-29-9)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-phenylpentanedinitrile (CAS 339030-16-9)
- Potassium 2,2-Dimethyl-1,3-dioxolane-4-carboxylate (CAS 83400-91-3)
- Pemafibrate Impurity 15 (CAS CATO-C4X-290315)
- β-Bag Cell Peptide (Aplysia californica) (CAS 109024-47-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com