1-(5-Fluoropyridin-2-yl)-1h-pyrazole-3-carboxylic acid CAS 1342829-19-9
| CAS No. | 1342829-19-9 |
| Molecular Formula | C9H6FN3O2 |
| Molecular Weight | 207.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(5-Fluoropyridin-2-yl)-1h-pyrazole-3-carboxylic acid (CAS 1342829-19-9), molecular formula C9H6FN3O2 and molecular weight 207.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(5-Fluoropyridin-2-yl)-1h-pyrazole-3-carboxylic acid (C9H6FN3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(5-Fluoropyridin-2-yl)-1h-pyrazole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6FN3O2 |
| Molecular Weight | 207.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluoropyridin Standards
- 2-[1-(5-Fluoropyridin-2-yl)-1H-pyrazol-4-yl]ethanol (CAS 1269382-44-6)
- {[3-(5-fluoropyridin-3-yl)-1h-pyrazol-4-yl]methyl}(methyl)amine (CAS 1513064-94-2)
- Bis(2-fluoropyridin-3-yl)methane (CAS 1245648-06-9)
- 2-(3-Fluoropyridin-2-yl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1431728-45-8)
- 5-(5-Fluoropyridin-2-yl)isoxazole-3-carboxylic acid (CAS 1547299-34-2)
- 3-(2-Fluoropyridin-4-yl)piperidine-2,6-dione (CAS 2858742-04-6)
- (S)-2-(5-fluoropyridin-2-yl)-4-isopropyl-4,5-dihydrooxazole (CAS 2757083-15-9)
- 5-(3-Fluoropyridin-4-yl)-1,2,4-oxadiazole-3-carboxylic acid (CAS 1489985-41-2)
Recommended Standards
- 6-Fluoro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (CAS 130064-10-7)
- 2-Fluoro-4-(4H-1,2,4-triazol-4-yl)benzoic acid (CAS 1351382-30-3)
- 3-Fluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acid (CAS 1293284-51-1)
- 7-fluoro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (CAS 136825-76-8)
- (R)-tert-Butyl pyrrolidine-2-carboxylate hydrochloride (CAS 184719-80-0)
- 1-[2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propan-1-one (CAS 1365803-10-6)
- 2-(2-Bromo-3-methylphenyl)ethan-1-ol (CAS 248920-15-2)
- (S)-Methyl 2-(((benzyloxy)carbonyl)(methyl)amino)-4-methylpentanoate (CAS 53363-88-5)
- 4',6-Bis(trifluoromethyl)-[1,1'-biphenyl]-2-carboxylic acid (CAS 1261733-06-5)
- 2-(3-(2-Methoxyphenyl)-6-oxopyridazin-1(6H)-yl)acetic acid (CAS 1286724-41-1)
- (1-Aminocyclopentyl)methyl hydrogen sulfate (CAS 10316-99-1)
- tert-butyl tert-butyl(2-(methoxy(methyl)amino)-2-oxoethyl)carbamate (CAS CATO-C3D-5416)
- 565-71-9 Isoserine Propanoic acid, 3-amino-2-hydroxy- 2-Hydroxy-3-aminopropanoic acid (CAS 565-71-9)
- Experimental Allergic Encephalitogenic Peptide (CAS 29705-92-8)
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