5-(O-tolylamino)thiazole-4-carboxylic acid CAS 1342850-07-0
| CAS No. | 1342850-07-0 |
| Molecular Formula | C11H10N2O2S |
| Molecular Weight | 234.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-(O-tolylamino)thiazole-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-(O-tolylamino)thiazole-4-carboxylic acid (CAS 1342850-07-0), molecular formula C11H10N2O2S and molecular weight 234.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(O-tolylamino)thiazole-4-carboxylic acid (C11H10N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H10N2O2S |
| Molecular Weight | 234.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related O Standards
- 2-(O-tolylamino)thiazole-4-carboxylic acid (CAS 165682-76-8)
- 2-(m-Tolylamino)thiazole-4-carboxylic acid (CAS 165682-77-9)
- 1-(m-Tolylamino)cyclohexanecarboxylic acid (CAS 725234-57-1)
- 1-(o-Tolylamino)cyclohexanecarboxylic acid (CAS 725234-58-2)
- 1-(P-tolylamino)cyclohexane-1-carboxylic acid (CAS 99216-79-2)
- 1-(2-(M-tolylamino)thiazol-5-yl)ethan-1-one (CAS 478078-69-2)
- 2-(M-tolylamino)nicotinic acid (CAS 57978-46-8)
- 2-(P-tolylamino)nicotinic acid (CAS 60645-32-1)
Recommended Standards
- 2-[methyl(phenyl)amino]-1,3-thiazole-5-carboxylic acid (CAS 1339523-57-7)
- 5-(3-(Hydroxymethyl)phenyl)thiophene-2-carboxylic acid (CAS 1349715-82-7)
- 3-((Thiazol-5-ylmethyl)amino)benzoic acid (CAS 1339490-87-7)
- 3-(3-(Hydroxymethyl)phenyl)thiophene-2-carboxylic acid (CAS 1349715-93-0)
- D-[1-18O]glucose (CAS 3343-70-2)
- 1-(2-(2,6-Dichlorophenyl)-1-hydroxyethyl)-2-phenylpyrazolidin-3-one (CAS 60260-70-0)
- 1-(4-Tert-butylphenyl)-2,5-dimethyl-1h-pyrrole-3-carbaldehyde (CAS 428488-10-2)
- 2-(Cyclopentyloxy)-5-methylpyridine-3-boronic acid (CAS 2096329-56-3)
- 1-(10H-phenothiazin-10-yl)-2-((5-(o-tolyl)-1,3,4-oxadiazol-2-yl)thio)ethan-1-one (CAS 332357-74-1)
- 1-(3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl)ethan-1-one (CAS 244187-01-7)
- N-Chloroacetyl-DL-valine (CAS 4090-17-9)
- Ethyl 2-(4-Chlorophenyl)acetate (CAS 14062-24-9)
- {2-[(2,4-dichlorophenyl)sulfanyl]pyridin-3-yl}methyl N-(4-chlorophenyl)carbamate (CAS 339278-59-0)
- Liraglutide Impurity 17 TFA Salt (CAS CATO-C4X-199217)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com