2-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]-4-methylpyridine CAS 1342880-67-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]-4-methylpyridine.

CATO supplies 2-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]-4-methylpyridine (CAS 1342880-67-4), a certified reference material (molecular formula C9H18ClN3O, MW 219.71 g/mol) for analytical method development and quality control.

The molecular framework of 2-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]-4-methylpyridine (C9H18ClN3O) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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