6-Bromo-8-chloro-2,2-dimethyl-3,4-dihydro-2h-1-benzopyran-4-one CAS 1342961-29-8
| CAS No. | 1342961-29-8 |
| Molecular Formula | C11H10BrClO2 |
| Molecular Weight | 289.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Bromo-8-chloro-2,2-dimethyl-3,4-dihydro-2h-1-benzopyran-4-one (C11H10BrClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
6-Bromo-8-chloro-2,2-dimethyl-3,4-dihydro-2h-1-benzopyran-4-one (CAS 1342961-29-8) is a high-purity analytical reference standard with the molecular formula C11H10BrClO2 and a molecular weight of 289.55 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Bromo-8-chloro-2,2-dimethyl-3,4-dihydro-2h-1-benzopyran-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10BrClO2 |
| Molecular Weight | 289.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/Br-containing |
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