1-(2,2-Difluoroethyl)azetidin-3-ol CAS 1343061-06-2
| CAS No. | 1343061-06-2 |
| Molecular Formula | C5H9F2NO |
| Molecular Weight | 137.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2,2-Difluoroethyl)azetidin-3-ol.
1-(2,2-Difluoroethyl)azetidin-3-ol (CAS 1343061-06-2), molecular formula C5H9F2NO and molecular weight 137.13 g/mol, is a CATO reference standard with documented purity and traceability.
1-(2,2-Difluoroethyl)azetidin-3-ol (C5H9F2NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(2,2-Difluoroethyl)azetidin-3-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H9F2NO |
| Molecular Weight | 137.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoroethyl Standards
- 3-(1,1-difluoroethyl)-1H-1,2,4-triazole (CAS 1202645-15-5)
- 1-(2,2-Difluoroethyl)azetidin-3-amine (CAS 1343973-39-6)
- N-(2,2-difluoroethyl)azetidin-3-amine (CAS 1550039-26-3)
- 3-(2,2-Difluoroethyl)cyclobutan-1-ol (CAS 1779935-03-3)
- (1-(1,1-Difluoroethyl)cyclopropyl)methanol (CAS 1780526-08-0)
- 3-(1,1-Difluoroethyl)cyclobutan-1-ol (CAS 2358391-50-9)
- N-(2,2-difluoroethyl)cyclobutanamine (CAS 1010189-79-3)
- (2,2-Difluoroethyl)glycine (CAS 1179601-53-6)
Recommended Standards
- 3-(2,2-Difluoroethoxy)azetidine (CAS 1342279-77-9)
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- (4,4-Difluoropyrrolidin-2-yl)methanol (CAS 1334488-61-7)
- 3-(Difluoromethyl)morpholine (CAS 1393554-05-6)
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