5-Amino-2-[(4-nitrophenyl)amino]-1,3-thiazole-4-carbonitrile CAS 134312-09-7

Purity 97%+In StockPharmaceutical Standards
CAS No.134312-09-7
Molecular FormulaC10H7N5O2S
Molecular Weight261.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Amino-2-[(4-nitrophenyl)amino]-1,3-thiazole-4-carbonitrile CAS 134312-09-7 chemical structure

Description

The occurrence of 5-Amino-2-[(4-nitrophenyl)amino]-1,3-thiazole-4-carbonitrile is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-Amino-2-[(4-nitrophenyl)amino]-1,3-thiazole-4-carbonitrile (CAS 134312-09-7) is a high-purity analytical reference standard with the molecular formula C10H7N5O2S and a molecular weight of 261.26 g/mol.

The molecular framework of 5-Amino-2-[(4-nitrophenyl)amino]-1,3-thiazole-4-carbonitrile (C10H7N5O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Amino-2-[(4-nitrophenyl)amino]-1,3-thiazole-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H7N5O2S
Molecular Weight261.26 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Nitrogen Atoms5
Sulfur Atoms1

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