2-(Chloromethyl)-1,3-difluoro-5-nitrobenzene CAS 1343441-16-6
| CAS No. | 1343441-16-6 |
| Molecular Formula | C7H4ClF2NO2 |
| Molecular Weight | 207.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 207.56 g/mol gives 2-(Chloromethyl)-1,3-difluoro-5-nitrobenzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(Chloromethyl)-1,3-difluoro-5-nitrobenzene (CAS 1343441-16-6) is a high-purity analytical reference standard with the molecular formula C7H4ClF2NO2 and a molecular weight of 207.56 g/mol.
Based on its molecular formula C7H4ClF2NO2, 2-(Chloromethyl)-1,3-difluoro-5-nitrobenzene contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 207.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4ClF2NO2 |
| Molecular Weight | 207.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- 1-(Chloromethyl)-2,5-difluoro-3-nitrobenzene (CAS 1803730-72-4)
- 2-(Chloromethyl)-3,5-diamino-4-(difluoromethyl)pyridine (CAS 1804986-57-9)
- 4-(Chloromethyl)-2-(difluoromethyl)-3-methoxypyridine (CAS 1805006-63-6)
- 2-(Chloromethyl)-4,5-diamino-3-(difluoromethyl)pyridine (CAS 1805038-01-0)
- 2-(Chloromethyl)-6-(difluoromethyl)-4-hydroxy-3-methylpyridine (CAS 1805200-39-8)
- 2-(Chloromethyl)-3,6-diamino-5-(difluoromethyl)pyridine (CAS 1805321-84-9)
- 2-(Chloromethyl)-4-(difluoromethyl)-6-methoxypyridine (CAS 1805323-03-8)
- 2-(Chloromethyl)-6-(difluoromethyl)pyridine-3-methanol (CAS 1805336-08-6)
Recommended Standards
- 1-Chloro-3-(difluoromethyl)-2-nitrobenzene (CAS 1261647-74-8)
- 3-Chloro-5-(difluoromethyl)picolinic acid (CAS 1386986-40-8)
- 4-Chloro-1-(difluoromethyl)-2-nitrobenzene (CAS 1261525-41-0)
- 2-(5-Chloropyridin-2-yl)-2,2-difluoroacetic acid (CAS 1783941-90-1)
- Tert-butyl 4-(3-bromo-5-nitropyridin-4-yl)piperazine-1-carboxylate (CAS 1407516-48-6)
- 1-(3-Methylbenzoyl)piperidine-4-carboxamide (CAS 418777-87-4)
- Methyl 3-(2-nitrophenoxy)thiophene-2-carboxylate (CAS 91041-18-8)
- Oleanolic Aldehyde (CAS 17020-22-3)
- Perampanel Impurity 35 (CAS CATO-C4X-243035)
- ethyl 3-bromo-5-(chlorosulfonyl)-2-methylbenzoate (CAS 1498463-61-8)
- Dimethyl 2-(1-(4-chlorophenyl)-2-nitroethyl)malonate (CAS 360072-54-4)
- Ethyl 2-(4-(ethylsulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)acetate (CAS 1707374-67-1)
- 6,6'-Dibromo-[2,2'-biindolinylidene]-3,3'-dione (CAS 19201-53-7)
- Met(O)14-Exenatide trifluoroacetate salt (CAS 1678417-38-3)
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