1-[1-methyl-2-(thiophen-2-yl)piperidin-3-yl]methanamine CAS 1343496-67-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[1-methyl-2-(thiophen-2-yl)piperidin-3-yl]methanamine.

1-[1-methyl-2-(thiophen-2-yl)piperidin-3-yl]methanamine (CAS 1343496-67-2), molecular formula C11H18N2S and molecular weight 210.34 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, 1-[1-methyl-2-(thiophen-2-yl)piperidin-3-yl]methanamine is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 210.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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