3-Cyclohexyl-4,4,4-trifluorobutanoic acid CAS 1343620-42-7
| CAS No. | 1343620-42-7 |
| Molecular Formula | C10H15F3O2 |
| Molecular Weight | 224.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3-Cyclohexyl-4,4,4-trifluorobutanoic acid (CAS 1343620-42-7), a certified reference material (molecular formula C10H15F3O2, MW 224.22 g/mol) for analytical method development and quality control.
The molecular framework of 3-Cyclohexyl-4,4,4-trifluorobutanoic acid (C10H15F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H15F3O2 |
| Molecular Weight | 224.22 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Cyclohexyl Standards
- Cyclohexyl(2,5-difluorophenyl)methanone (CAS 1094338-35-8)
- Cyclohexyl(2,6-difluorophenyl)methanone (CAS 1342160-28-4)
- Cyclohexyl(2,3-difluorophenyl)methanone (CAS 1344347-07-4)
- Cyclohexyl(2,4-difluorophenyl)methanone (CAS 898769-54-5)
- Cyclohexyl(3,4-difluorophenyl)methanone (CAS 898769-56-7)
- Cyclohexyl(3,5-difluorophenyl)methanone (CAS 898769-58-9)
- 3-(3-Cyclohexyl-1,2,4-oxadiazol-5-yl)propanoic acid (CAS 1152535-96-0)
- Ethyl 5-cyclohexyl-1,2,4-oxadiazole-3-carboxylate (CAS 1343186-43-5)
Recommended Standards
- 2-methyl-N’-(5-nitropyridin-2-yl)propanehydrazide (CAS 1329296-85-6)
- 1-(1-Methyl-4-nitro-1H-pyrazol-5-yl)piperidin-4-one (CAS 1428574-05-3)
- 1-(5-Nitropyrimidin-2-yl)piperidin-3-ol (CAS 1250542-21-2)
- (1H-benzo[d][1,2,3]triazol-1-yl)(pyridin-2-yl)methanone (CAS 144223-29-0)
- tert-Butyl N-[3-(1,3-oxazol-5-yl)phenyl]carbamate (CAS 1483530-03-5)
- 5-(Piperazin-1-yl)pyridine-2-carbonitrile dihydrochloride (CAS 1427381-10-9)
- 2-(4-Methyl-6-(pyridin-2-yl)pyrimidin-2-yl)ethan-1-amine hydrochloride (CAS 1196155-36-8)
- 6-(5-chlorothiophen-2-yl)pyridin-3-amine (CAS 438585-65-0)
- Ethyl 7-bromo-5-chloro-1H-indole-2-carboxylate (CAS 1352896-41-3)
- 2-Chloro-N6-furfuryladenine (CAS 101862-47-9)
- 5-Ethoxy-1,2-dimethyl-1H-indole-3-carbaldehyde (CAS 876715-28-5)
- 2-Chloro-4-(1h-pyrazol-1-yl)pyrimidine (CAS 1247815-03-7)
- (R)-1-Benzyl-3-bromopiperidine (CAS 1353997-04-2)
- Liraglutide Impurity 31 (CAS CATO-C4X-199231)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com