1-Methyl-3-(trifluoromethyl)pyrrolidine-3-carboxylic acid CAS 1343629-94-6
| CAS No. | 1343629-94-6 |
| Molecular Formula | C7H10F3NO2 |
| Molecular Weight | 197.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-Methyl-3-(trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1343629-94-6), molecular formula C7H10F3NO2 and molecular weight 197.16 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 1-Methyl-3-(trifluoromethyl)pyrrolidine-3-carboxylic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 197.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 1-Methyl-3-(trifluoromethyl)pyrrolidine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H10F3NO2 |
| Molecular Weight | 197.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 6-(Trifluoromethyl)piperidine-3-carboxylic acid (CAS 1155103-14-2)
- Methyl 4-(trifluoromethyl)pyrrolidine-3-carboxylate (CAS 1190043-09-4)
- 7-(Trifluoromethyl)isoquinoline (CAS 1194375-56-8)
- 6-(Trifluoromethyl)isoquinoline (CAS 1194375-62-6)
- 4-(Trifluoromethyl)isoquinoline (CAS 120568-08-3)
- 8-(trifluoromethyl)isoquinoline (CAS 120568-10-7)
- 2-(Trifluoromethyl)piperidine-3-carboxylic acid (CAS 1240528-93-1)
- 2-(5-(Trifluoromethyl)pyrrolidin-2-yl)acetic acid (CAS 1258640-31-1)
Recommended Standards
- 1-(2,2,2-Trifluoroethyl)pyrrolidine-3-carboxylic acid (CAS 1343213-71-7)
- (2R,4S)-4-(trifluoromethyl)piperidine-2-carboxylic acid (CAS 1350632-24-4)
- 2-(1-(2,2,2-Trifluoroethyl)azetidin-3-yl)acetic acid (CAS 1341888-85-4)
- Ethyl 2-(5-fluoropyridin-2-yl)-2-oxoacetate (CAS 1352129-99-7)
- 3-Bromo-4-(4-chlorophenyl)-6-methylpyridin-2-amine (CAS 1774904-14-1)
- Benzenemethanamine, 4-amino-N-(2-fluorophenyl)- (CAS 1538115-58-0)
- 2-(4-Propoxyphenoxy)cyclohexan-1-amine hydrochloride (CAS 1315368-62-7)
- N-[(3-Chlorophenyl)methyl]-N-(2-{N-[(3-chlorophenyl)methyl]-1-(4-methylphenyl)formamido}ethyl)-4-methylbenzamide (CAS 338775-04-5)
- 2-(Methylthio)-3-(4-(3-(4-phenylpiperazin-1-yl)propoxy)phenyl)pyrimidin-4(3H)-one (CAS 119321-60-7)
- 5-Bromo-6-chloro-4-methylpyridine-3-carbonitrile (CAS 2090170-50-4)
- (4-Bromo-2-chlorophenyl)boronic acid (CAS 1046861-20-4)
- (R)-6-Chloro-2,3-dihydrobenzofuran-3-amine hydrochloride (CAS 2102411-86-7)
- 5-(Dimethylamino)pentanenitrile hydrobromide (CAS 1051369-00-6)
- D-allo-Thr7-Semaglutide (CAS CATO-C4X-2226242)
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