3-(4-Methylphenyl)-1,2-oxazole-5-carboxylic acid CAS 134378-95-3
| CAS No. | 134378-95-3 |
| Molecular Formula | C11H9NO3 |
| Molecular Weight | 203.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(4-Methylphenyl)-1,2-oxazole-5-carboxylic acid.
3-(4-Methylphenyl)-1,2-oxazole-5-carboxylic acid (CAS 134378-95-3), molecular formula C11H9NO3 and molecular weight 203.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(4-Methylphenyl)-1,2-oxazole-5-carboxylic acid (C11H9NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9NO3 |
| Molecular Weight | 203.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 1 |
Related Methylphenyl Standards
- 5-(2-Methylphenyl)isoxazole-3-carboxylic acid (CAS 668970-80-7)
- 5-(3-Methylphenyl)-1,2-oxazole-3-carboxylic acid (CAS 887979-11-5)
- 5-(4-Methylphenyl)-1,3-oxazole-4-carboxylic acid (CAS 89205-04-9)
- 5-(4-Methylphenyl)isoxazole-3-carboxylic acid (CAS 33282-21-2)
- 2-(3-methylphenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1042655-56-0)
- 1-(2-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1099631-80-7)
- 1-(4-Methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 113934-31-9)
- 1-(3-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 944901-55-7)
Recommended Standards
- 2,5-Difluoro-4-(2-methoxyethoxy)aniline (CAS 1342588-84-4)
- 5-(Phenylmethyl)-2-oxazolecarboxylic Acid (CAS 1357955-62-4)
- 2-Methyl-3-(prop-2-ynoylamino)benzoic acid (CAS 1342365-77-8)
- 5-Methoxyquinoline-3-carboxylic Acid (CAS 1361091-98-6)
- (2-Chloro-4-methoxypyridin-3-yl)methanol (CAS 1378822-82-2)
- 3-(tert-Butoxy)-5-cyclopropoxyisonicotinamide (CAS 1243285-52-0)
- 1338494-91-9 Ethyl [2-(cyanoamino)-4-hydroxypyrimidin-5-yl]acetate MFCD20441410 (CAS 1338494-91-9)
- 4,4-dimethyl-1-[(1-methylpiperidin-4-yl)amino]pentan-2-ol (CAS 1803610-16-3)
- Tert-butyl ((4-(aminomethyl)-2-oxabicyclo[2.1.1]Hexan-1-yl)methyl)carbamate (CAS 2260936-16-9)
- 2-Fluoro-5-methyl-4-phenylpyridine (CAS 1806475-54-6)
- 4-Bromo-6-fluoro-2-methylquinoline (CAS 1070879-47-8)
- Nicorandil Impurity 45 formate salt (CAS 2365474-05-9（free base）)
- Teneligliptin (2S,4R)-Isomer 2.5HBr (CAS CATO-C4X-176052)
- Semaglutide impurity 60 (CAS CATO-C4X-222660)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com