3-(Trifluoromethyl)-1H-indene CAS 134391-57-4
| CAS No. | 134391-57-4 |
| Molecular Formula | C10H7F3 |
| Molecular Weight | 184.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(Trifluoromethyl)-1H-indene is closely related to fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(Trifluoromethyl)-1H-indene (CAS 134391-57-4), molecular formula C10H7F3 and molecular weight 184.16 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to fluorine substitution, an aromatic ring system, 3-(Trifluoromethyl)-1H-indene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(Trifluoromethyl)-1H-indene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7F3 |
| Molecular Weight | 184.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
Related Trifluoromethyl Standards
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- 4-Methyl-3-(trifluoromethyl)pentanoic acid (CAS 184876-90-2)
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- 6-(TRIFLUOROMETHYL)-1H-INDENE (CAS 321937-10-4)
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- 2-(trifluoromethyl)-3,4-dihydro-2H-thiopyran-4-ol (CAS 1803592-09-7)
Recommended Standards
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