2-Chloro-5-(1,2-oxazol-3-yl)-1,3,4-thiadiazole CAS 1343912-53-7
| CAS No. | 1343912-53-7 |
| Molecular Formula | C5H2ClN3OS |
| Molecular Weight | 187.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Chloro-5-(1,2-oxazol-3-yl)-1,3,4-thiadiazole (CAS 1343912-53-7), a certified reference material (molecular formula C5H2ClN3OS, MW 187.61 g/mol) for analytical method development and quality control.
2-Chloro-5-(1,2-oxazol-3-yl)-1,3,4-thiadiazole (C5H2ClN3OS) contains an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-5-(1,2-oxazol-3-yl)-1,3,4-thiadiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H2ClN3OS |
| Molecular Weight | 187.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 7-Chlorothiazolo[5,4-d]pyrimidin-2-ol (CAS 120209-33-8)
- 2-(2-Amino-4-chlorophenoxy)ethan-1-ol (CAS 1020970-86-8)
- 5-Chlorothiazolo[5,4-d]pyrimidin-2(1H)-one (CAS 120209-32-7)
- 2-(Chloromethyl)-4,6-dimethoxypyridine (CAS 1056894-51-9)
- 1-ethyl-1,4-diazepan-2-one (CAS 1543092-05-2)
- (3R,5S)-5-methylpyrrolidin-3-amine dihydrobromide (CAS 144043-31-2)
- 4-(Difluoromethyl)-2,3-diiodo-5-methylpyridine (CAS 1805010-89-2)
- Tezacaftor Metabolite M1 (CAS 1432657-04-9)
- N-(2-Nitro-4-(pyrazin-2-ylthio)phenyl)acetamide (CAS 55564-28-8)
- 3-(Bromomethyl)-9,10-dioxo-9,10-dihydroanthracene-1,8-diyl diacetate (CAS 65615-59-0)
- 1-Benzyl-4-methyl-1H-pyrazol-5-amine (CAS 3528-49-2)
- 3-Iodo-5-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 1000343-70-3)
- 4-(4-Chlorophenyl)-2-(4-methylphenyl)-4-oxobutanoic acid (CAS 70596-90-6)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
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