Finerenone Impurity 244 CAS 13444-19-4
| CAS No. | 13444-19-4 |
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Finerenone Impurity 244 (C11H12O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Finerenone Impurity 244 (CAS 13444-19-4, C11H12O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥98% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
Related Finerenone Standards
- Finerenone Impurity 249 (CAS CATO-C4X-2880249)
- Finerenone Impurity 28 (CAS 220389-16-2)
- Finerenone Impurity 205 (CAS 890705-78-9)
- Finerenone Impurity 166 (CAS CATO-C4X-2880166)
- Finerenone Impurity 171 (CAS CATO-C4X-2880171)
- Finerenone Impurity 143 (CAS CATO-C4X-2880143)
- Finerenone Impurity 144 (CAS CATO-C4X-2880144)
- Finerenone Impurity 145 (CAS CATO-C4X-2880145)
Recommended Standards
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- Ilaprazole Impurity 42 (CAS 2288740-67-8)
- Resmetirom Impurity 29 (CAS CATO-C4X-291229)
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