(R)-3-Amino-2-oxo-4-(trifluoromethyl)indoline-3-carboxylic acid CAS 1344492-99-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1344492-99-4
Molecular FormulaC10H7F3N2O3
Molecular Weight260.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(R)-3-Amino-2-oxo-4-(trifluoromethyl)indoline-3-carboxylic acid CAS 1344492-99-4 chemical structure

Description

(R)-3-Amino-2-oxo-4-(trifluoromethyl)indoline-3-carboxylic acid (CAS 1344492-99-4), molecular formula C10H7F3N2O3 and molecular weight 260.17 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, (R)-3-Amino-2-oxo-4-(trifluoromethyl)indoline-3-carboxylic acid (C10H7F3N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 260.17 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H7F3N2O3
Molecular Weight260.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF-containing
Nitrogen Atoms2

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