(R)-2-(3-bromo-5-chloro-2-fluorophenyl)pyrrolidine CAS 1344546-91-3
| CAS No. | 1344546-91-3 |
| Molecular Formula | C10H10BrClFN |
| Molecular Weight | 278.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (R)-2-(3-bromo-5-chloro-2-fluorophenyl)pyrrolidine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (R)-2-(3-bromo-5-chloro-2-fluorophenyl)pyrrolidine (CAS 1344546-91-3), a certified reference material (molecular formula C10H10BrClFN, MW 278.55 g/mol) for analytical method development and quality control.
The molecular framework of (R)-2-(3-bromo-5-chloro-2-fluorophenyl)pyrrolidine (C10H10BrClFN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (R)-2-(3-bromo-5-chloro-2-fluorophenyl)pyrrolidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10BrClFN |
| Molecular Weight | 278.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- 5-bromo-2-chloro-6-methoxybenzo[d]thiazole, 97% (CAS 1247348-76-0)
- (R)-2-(4-bromo-2-chloro-5-fluorophenyl)pyrrolidine (CAS 1335813-73-4)
- (S)-2-(4-bromo-2-chloro-5-fluorophenyl)pyrrolidine (CAS 1336723-71-7)
- (S)-2-(2-bromo-6-chloro-3-fluorophenyl)pyrrolidine (CAS 1344402-77-2)
- (R)-2-(2-bromo-6-chloro-3-fluorophenyl)pyrrolidine (CAS 1344437-97-3)
- (S)-2-(3-bromo-5-chloro-2-fluorophenyl)pyrrolidine (CAS 1344446-37-2)
- (R)-2-(6-bromo-2-chloro-3-fluorophenyl)pyrrolidine (CAS 1344454-80-3)
- (S)-2-(6-bromo-2-chloro-3-fluorophenyl)pyrrolidine (CAS 1344458-03-2)
Recommended Standards
- (R)-2-(5-bromo-3-chloro-2-fluorophenyl)pyrrolidine (CAS 1344497-05-7)
- (S)-2-(5-bromo-4-chloro-2-fluorophenyl)pyrrolidine (CAS 1391388-19-4)
- (R)-2-(5-bromo-4-chloro-2-fluorophenyl)pyrrolidine (CAS 1391421-63-8)
- 2-Bromo-4-chloro-6-methoxybenzo[d]thiazole (CAS 1464091-50-6)
- 5-Chloro-4-(propylamino)pyridine-3-sulfonamide (CAS 1352531-06-6)
- (4-(Morpholinomethyl)phenyl)(p-tolyl)methanone (CAS 898769-66-9)
- (2-(Tetrahydro-2H-thiopyran-4-yl)thiazol-4-yl)methanol (CAS 1478716-69-6)
- N1,N1'-(propane-1,3-diyl)bis(ethane-1,2-diamine) tetrahydrochloride (CAS 73082-39-0)
- 2-((1H-Imidazol-4-yl)methyl)-2-amino-3-fluoropropanoic acid (CAS 70050-43-0)
- 1-(6-Bromo-3-pyridinyl)-4-methylpiperazine (CAS 879488-53-6)
- N-Acetyl-DL-tryptophan (CAS 87-32-1)
- 2-Acetyl-3'-(benzyloxy)biphenyl (CAS 893739-69-0)
- 2,3-Dimethylhexan-2-ol (CAS 19550-03-9)
- Des-Lys20(Side Chain)-Semaglutide (CAS CATO-C4X-2226280)
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