(2R)-2-(Fluoromethyl)piperidine CAS 1344580-68-2
| CAS No. | 1344580-68-2 |
| Molecular Formula | C6H12FN |
| Molecular Weight | 117.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 117.16 g/mol gives (2R)-2-(Fluoromethyl)piperidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(2R)-2-(Fluoromethyl)piperidine (CAS 1344580-68-2), molecular formula C6H12FN and molecular weight 117.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2R)-2-(Fluoromethyl)piperidine (C6H12FN) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H12FN |
| Molecular Weight | 117.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- 3-(Fluoromethyl)piperidine (CAS 116574-73-3)
- 2-(Fluoromethyl)piperidine (CAS 1240528-86-2)
- 1-[2-(fluoromethyl)cyclobutyl]methanamine (CAS 1421606-00-9)
- (R)-3-(fluoromethyl)piperidine (CAS 1444103-49-4)
- (2S)-2-(Fluoromethyl)piperidine (CAS 886358-35-6)
- (S)-3-(fluoromethyl)piperidine (CAS 2306246-72-8)
- 4-(Fluoromethyl)piperidine (CAS 259143-04-9)
- (R)-5-(Fluoromethyl)pyrrolidin-2-one (CAS 1412816-93-3)
Recommended Standards
- 4-Fluorocyclohexan-1-amine (CAS 1314924-99-6)
- 3-Fluoro-3-methylpiperidine (CAS 1374657-04-1)
- (1S,2R)-2-fluorocyclohexan-1-amine (CAS 1290191-94-4)
- 3-Fluoro-4-methylpiperidine (CAS 1379377-35-1)
- n-Propyl-1,3-thiazol-2-amine (CAS 78508-32-4)
- 3-Bromo-5-chloro-2,6-difluorophenylboronic acid (CAS 1451393-03-5)
- 2-[2-(Trifluoromethyl)phenyl]cyclopropanecarboxylic Acid (CAS 1187933-13-6)
- (R)-2-Amino-3-cyclobutylpropan-1-ol (CAS 1213152-74-9)
- Ethyl 3-amino-3-(pyridin-2-yl)propanoate (CAS 77742-21-3)
- 3-Fluoro-2-(4-fluorophenyl)-5-(trifluoromethyl)pyridine (CAS 1214342-33-2)
- 1-(6-(Trifluoromethyl)pyridin-3-yl)cyclopropane-1-carboxylic acid (CAS 1060811-01-9)
- n-(2-Methoxyethyl)-5-nitropyridin-2-amine (CAS 74037-56-2)
- 4-Propyl-1H-indol-5-ol (CAS 724466-38-0)
- (Tyr9)-Cholecystokinin Octapeptide (sulfated) (H-9770.0005) (CAS 96607-61-3)
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