5-Fluorobenzoxazole-2(3H)-thione CAS 13451-78-0
| CAS No. | 13451-78-0 |
| Molecular Formula | C7H4FNOS |
| Molecular Weight | 169.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 5-Fluorobenzoxazole-2(3H)-thione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
5-Fluorobenzoxazole-2(3H)-thione (CAS 13451-78-0) is a high-purity analytical reference standard with the molecular formula C7H4FNOS and a molecular weight of 169.18 g/mol.
The molecular framework of 5-Fluorobenzoxazole-2(3H)-thione (C7H4FNOS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H4FNOS |
| Molecular Weight | 169.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fluorobenzoxazole Standards
- 6-Fluorobenzoxazole-2(3H)-thione (CAS 145096-57-7)
- 7-Fluorobenzoxazole-2(3H)-thione (CAS 153403-54-4)
- 4-Fluorobenzoxazole-2-methanamine (CAS 944897-61-4)
- 5-Fluorobenzoxazole-2-methanamine (CAS 944907-48-6)
- 6-Fluorobenzoxazole-2-methanamine (CAS 944907-47-5)
- 7-Fluorobenzoxazole-2-methanamine (CAS 944903-15-5)
- 2-Ethyl-5-fluorobenzoxazole (CAS 1267772-21-3)
- 7-Fluorobenzoxazole (CAS 1267061-18-6)
Recommended Standards
- (S)-2-Amino-3-(1-methyl-1H-pyrazol-4-yl)propanoic acid (CAS 1344937-42-3)
- Ethyl 5-ethylisoxazole-4-carboxylate (CAS 134540-94-6)
- 2-(1-Aminopropyl)-1h-imidazole-5-carboxylic acid (CAS 1344701-78-5)
- 5-(Tert-butyl)isoxazole-4-carboxylic acid (CAS 134541-06-3)
- 4-(4-Aminophenyl)benzonitrile (CAS 4854-84-6)
- 3-(2,5-Dimethoxyphenyl)-1-phenyl-1h-pyrazole-4-carbaldehyde (CAS 956206-42-1)
- (3aR,8aS)-3,3a,8,8a-Tetrahydro-2H-indeno[1,2-d]oxazol-2-one (CAS 135969-65-2)
- 6-[[(3-Tetrahydrofuranyl)oxy]methyl]pyridine-2-methanamine Dihydrochloride (CAS 2044796-66-7)
- Salbutamol Impurity 125 (CAS CATO-C4X-1176125)
- Ethyl 4-((3-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-3-yl)phenyl)amino)-4-oxobutanoate (CAS 1396759-46-8)
- Abemaciclib Impurity 79 (CAS CATO-C4X-293779)
- 3-(5-Bromo-2-fluorobenzyl)azetidin-3-ol (CAS 1489495-10-4)
- (1Z)-1-[4-(1H-Pyrrol-1-yl)phenyl]ethanone oxime (CAS 832738-15-5)
- Insulin Degludec Impurity 6 (CAS CATO-C4X-21576)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com