Ethambutol EP Impurity C DiHCl CAS 134566-79-3
| CAS No. | 134566-79-3 |
| Molecular Formula | C10H24N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ethambutol EP Impurity C DiHCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Ethambutol EP Impurity C DiHCl (CAS 134566-79-3, C10H24N2O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ethambutol EP Impurity C DiHCl (C10H24N2O2HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of -1.0, corresponding to approximately 0 ring(s) or double-bond equivalent(s). With a molecular weight of 240.77 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C10H24N2O2 2*HCl |
| Molecular Weight | 240.77 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | -1.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ethambutol Standards
- Ethambutol EP Impurity C (2R,2’R-Ethambutol) (CAS 10054-05-4)
- Ethambutol EP Impurity B (CAS 10054-06-5)
- Ethambutol dihydrochloride (CAS 1070-11-7)
- Ethambutol-d4 Dihydrochloride (CAS 1129526-19-7)
- Ethambutol-d8 (CAS 1129526-23-3)
- Ethambutol Impurity 8 (CAS 2792161-95-4)
- Ethambutol EP Impurity B (2R,2’S-Ethambutol) DiHCl (CAS 32454-69-6)
- Ethambutol Impurity 7(Mixture of Diastereomers) (CAS 498-17-9)
Recommended Standards
- Raloxifene Impurity N65 (CAS 63675-73-0)
- Posaconazole Impurity 109 (CAS CATO-C4X-1208109)
- Sodium Cromoglicate Impurity 18 (CAS CATO-C4X-201118)
- 7-Chloroimidazo[1,2-a]pyridine, HCl (CAS 1072944-43-4)
- 2,6-Difluorobenzenethiol (CAS 172366-44-8)
- 5-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-1-propyl-1H-pyrazole (CAS 1487355-92-9)
- 8-bromo-3-fluoro-chromen-4-one (CAS 2761011-98-5)
- Voriconazole Impurity 85 (CAS CATO-C4X-136685)
- 2-(Allylthio)-6-aminopyrimidin-4(3H)-one (CAS 57939-40-9)
- Tau Peptide (337-368) (Repeat 4 Domain) trifluoroacetate salt (CAS 330456-27-4)
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