6-Bromo-5-hydroxy-4-iodopicolinaldehyde CAS 1346447-15-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1346447-15-1
Molecular FormulaC6H3BrINO2
Molecular Weight327.90 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Bromo-5-hydroxy-4-iodopicolinaldehyde CAS 1346447-15-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 327.90 g/mol gives 6-Bromo-5-hydroxy-4-iodopicolinaldehyde distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 6-Bromo-5-hydroxy-4-iodopicolinaldehyde (CAS 1346447-15-1), a certified reference material (molecular formula C6H3BrINO2, MW 327.90 g/mol) for analytical method development and quality control.

The molecular framework of 6-Bromo-5-hydroxy-4-iodopicolinaldehyde (C6H3BrINO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Bromo-5-hydroxy-4-iodopicolinaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H3BrINO2
Molecular Weight327.90 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentBr/I-containing
Nitrogen Atoms1

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