tert-Butyl 5-bromo-2-methylnicotinate CAS 1346543-51-8
| CAS No. | 1346543-51-8 |
| Molecular Formula | C11H14BrNO2 |
| Molecular Weight | 272.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 272.14 g/mol gives tert-Butyl 5-bromo-2-methylnicotinate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies tert-Butyl 5-bromo-2-methylnicotinate (CAS 1346543-51-8), a certified reference material (molecular formula C11H14BrNO2, MW 272.14 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, tert-Butyl 5-bromo-2-methylnicotinate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 272.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures tert-Butyl 5-bromo-2-methylnicotinate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H14BrNO2 |
| Molecular Weight | 272.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Methyl (R)-3-amino-3-(3-bromo-5-methylphenyl)propanoate (CAS 1344413-33-7)
- 2,2,3,3,3-Pentafluoro-1-(5-fluoro-2-methoxyphenyl)propan-1-one (CAS 1352208-76-4)
- 3-(2-(3-Bromophenoxy)ethoxy)azetidine (CAS 1343908-70-2)
- (S)-2-Amino-N-((2-bromopyridin-4-yl)methyl)-N-methylpropanamide (CAS 1354008-27-7)
- 6-tert-Butyl 2-methyl 7,8-dihydropyrrolo-[3,2-e]indole-2,6(3H)-dicarboxylate (CAS 107474-66-8)
- Magnesium thiosulfate hexahydrate (CAS 13446-30-5)
- 3-Methyl 2H-Furo[2,3-c]pyran-2-one 857054-02-5 KAR1 Karrikinolide (CAS 857054-02-5)
- 2,2'-Oxybis(ethan-1-amine) diacetate (CAS 1375090-12-2)
- 2-(Bicyclo[2.2.2]Octan-1-yl)acetic acid (CAS 1895244-70-8)
- 2-(5-Bromo-1H-indazol-3-yl)ethanamine (CAS 910405-62-8)
- 1-(4-Chloro-2-nitrophenyl)-1H-pyrrole-2,5-dione (CAS 65833-07-0)
- Methyl 2-amino-3-hydroxybutanoate (CAS 2065185-81-9)
- 5-Chloro-2-cyanobenzenesulfonyl Chloride (CAS 411210-92-9)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com