4-Desmethoxy-4-bromo Trimethoprim-d3 CAS 1346600-27-8
| CAS No. | 1346600-27-8 |
| Molecular Formula | - |
| Molecular Weight | 342.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 4-Desmethoxy-4-bromo Trimethoprim-d3 (C13H12D3BrN4O2) contains deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.5, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 342.21 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 4-Desmethoxy-4-bromo Trimethoprim-d3 (CAS 1346600-27-8), a certified reference material (molecular formula C13H12D3BrN4O2, MW 342.21 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Desmethoxy-4-bromo Trimethoprim-d3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H12D3BrN4O2 |
| Molecular Weight | 342.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Desmethoxy Standards
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Recommended Standards
- 3-((4-Bromophenyl)sulfonyl)-4,6-dimethylpyridin-2(1h)-one (CAS 1334488-56-0)
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- 4-Bromo-3-methyl-1-tosyl-1H-pyrrole-2-carbaldehyde (CAS 1284257-69-7)
- N-(3-Bromo-4-phenoxyphenyl)methanesulfonamide, 97% (CAS 1445994-12-6)
- 2-chloro-N-[2-propoxy-5-(trifluoromethyl)phenyl]acetamide (CAS 885460-69-5)
- 1H-pyrrole-2,3-dicarboxylic acid (CAS 1125-32-2)
- 1,3-Cyclohexanedione, 5-[2-(ethylthio)propyl]-2-(1-oxopropyl)- (CAS 99422-01-2)
- Ethyl 2-bromo-4,5,6,7-tetrahydrobenzo[d]thiazole-4-carboxylate (CAS 729590-69-6)
- 2-(chlorosulfonyl)-1,3-dimethoxypropane (CAS 1871639-57-4)
- Rhodium(III) bromide dihydrate (CAS 76758-40-2)
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