4-O-tert-Butyldimethylsilyl-2-(hydroxymethyl)-3-methylpyridine CAS 1346604-38-3
| CAS No. | 1346604-38-3 |
| Molecular Formula | C13H23NO2Si |
| Molecular Weight | 253.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-O-tert-Butyldimethylsilyl-2-(hydroxymethyl)-3-methylpyridine (CAS 1346604-38-3), molecular formula C13H23NO2Si and molecular weight 253.41 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, 4-O-tert-Butyldimethylsilyl-2-(hydroxymethyl)-3-methylpyridine is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 253.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-O-tert-Butyldimethylsilyl-2-(hydroxymethyl)-3-methylpyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H23NO2Si |
| Molecular Weight | 253.41 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Recommended Standards
- rac Deoxy-O-desmethyl Venlafaxine-d6 (CAS 1346600-06-3)
- 2,2,6,6-Tetramethyl-N-(thiazol-5-ylmethyl)piperidin-4-amine (CAS 1491830-69-3)
- 1-(Trimethylsilyl)-5,6-dihydrobenzo[f]isoquinoline (CAS 131373-01-8)
- (6-(((tert-Butyldimethylsilyl)oxy)methyl)pyridin-2-yl)methanol (CAS 150058-64-3)
- 1-(3-(Tert-butyl)phenyl)-2,2,2-trifluoroethan-1-one (CAS 155628-03-8)
- N,1-Dicyclopropyl-4-piperidinamine (CAS 1285263-93-5)
- 4-Chloro-6-(1-ethyl-1H-pyrazol-3-yl)-2-(1-methoxyethyl)pyrimidine (CAS 1707579-43-8)
- tert-Butyl (2-(4-acetyl-6-iodopyridin-2-yl)ethyl)carbamate (CAS 1393573-25-5)
- 4-(4-(Tert-butoxycarbonyl)piperazin-1-yl)nicotinic acid (CAS 654663-41-9)
- 2-(2-Fluorophenoxy)benzaldehyde (CAS 82097-82-3)
- N'-(1-benzylpiperidine-4-carbonyl)-3-(2-chlorophenyl)-5-methylisoxazole-4-carbohydrazide (CAS 478064-37-8)
- 4-(4-Iodophenyl)-4-oxobutanoic acid (CAS 194146-02-6)
- 2-((2-Chloro-4-fluorobenzyl)oxy)-5-methylbenzaldehyde (CAS 1281726-96-2)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
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