3-Amino-4-(2-chlorophenyl)-6-nitro-2(1H)-quinolinone-d4 (Clonazepam Impurity) CAS 1346604-43-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1346604-43-0
Molecular Formula-
Molecular Weight319.74 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Amino-4-(2-chlorophenyl)-6-nitro-2(1H)-quinolinone-d4 (Clonazepam Impurity) CAS 1346604-43-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 319.74 g/mol gives 3-Amino-4-(2-chlorophenyl)-6-nitro-2(1H)-quinolinone-d4 (Clonazepam Impurity) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-Amino-4-(2-chlorophenyl)-6-nitro-2(1H)-quinolinone-d4 (Clonazepam Impurity) (CAS 1346604-43-0), molecular formula C15H6D4ClN3O3 and molecular weight 319.74 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 3-Amino-4-(2-chlorophenyl)-6-nitro-2(1H)-quinolinone-d4 (Clonazepam Impurity) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 319.74 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-Amino-4-(2-chlorophenyl)-6-nitro-2(1H)-quinolinone-d4 (Clonazepam Impurity) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H6D4ClN3O3
Molecular Weight319.74 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentCl-containing
Nitrogen Atoms3

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