2-Chloro-6-(2,2,2-trifluoroethoxy)pyridin-4-amine CAS 1346809-43-5
| CAS No. | 1346809-43-5 |
| Molecular Formula | C7H6ClF3N2O |
| Molecular Weight | 226.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-6-(2,2,2-trifluoroethoxy)pyridin-4-amine.
CATO supplies 2-Chloro-6-(2,2,2-trifluoroethoxy)pyridin-4-amine (CAS 1346809-43-5), a certified reference material (molecular formula C7H6ClF3N2O, MW 226.58 g/mol) for analytical method development and quality control.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 2-Chloro-6-(2,2,2-trifluoroethoxy)pyridin-4-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 226.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6ClF3N2O |
| Molecular Weight | 226.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
- 3-Chloro-5-(3,3,3-trifluoropropoxy)pyridazine (CAS 1346691-34-6)
- 3-Chloro-2-(methylamino)-5-(trifluoromethyl)pyridine 1-oxide (CAS 1379369-53-5)
- (2-Chloro-4-(trifluoromethoxy)phenyl)methanol (CAS 1261822-74-5)
- 6-Chloro-2-(2,2,2-trifluoroethoxy)pyridin-3-amine (CAS 1550595-82-8)
- 2-chloro-N-({3-[(2-ethoxyethoxy)methyl]phenyl}methyl)acetamide (CAS 1306605-63-9)
- (3-(4-Bromophenyl)-1-(4-fluorophenyl)-1H-pyrazol-4-yl)methanol (CAS 618441-65-9)
- 4-Bromo-2,3-difluoro-(n-hexyloxy)benzene (CAS 256383-40-1)
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- 2,2,2-trifluoroethyl N-(6-oxo-1-propyl-1,6-dihydropyridin-3-yl)carbamate (CAS 1333569-97-3)
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- 5-Piperidin-1-ylmethyl-furan-2-carboxylic acid 5-(piperidin-1-ylmethyl)furan-2-carboxylic acid 5-(1-piperidinylmethyl)-2-furoic acid 5-piperidin-1-ylmethylfuran-2-carboxylic acid 5-(piperidin-1-ylmethyl)-2-furoic acid 301353-36-6 (CAS 301353-36-6)
- 4-Chloro-2-(2-methoxyethyl)-6-(1-methyl-1H-pyrazol-4-yl)pyrimidine (CAS 1708199-18-1)
- Insulin Degludec Impurity 13 (CAS CATO-C4X-215713)
Why CATO?
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