2,4,6,8-Tetrachlorodibenzo[b,d]thiophene CAS 134705-49-0
| CAS No. | 134705-49-0 |
| Molecular Formula | C12H4Cl4S |
| Molecular Weight | 322.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,4,6,8-Tetrachlorodibenzo[b,d]thiophene (CAS 134705-49-0), molecular formula C12H4Cl4S and molecular weight 322.04 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,4,6,8-Tetrachlorodibenzo[b,d]thiophene (C12H4Cl4S) is characterized by sulfur-containing functionality, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H4Cl4S |
| Molecular Weight | 322.04 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Tetrachlorodibenzo Standards
- 2,3,7,8-Tetrachlorodibenzo[b,d]thiophene (CAS 133513-17-4)
- 3,4,6,7-Tetrachlorodibenzo[b,d]thiophene (CAS 133513-18-5)
- 2,3,6,7-Tetrachlorodibenzo[b,d]thiophene (CAS 133513-19-6)
- 1,4,6,9-Tetrachlorodibenzo[b,d]thiophene (CAS 134705-50-3)
- 1,3,7,9-Tetrachlorodibenzo[b,d]thiophene (CAS 134705-51-4)
- 1,3,7,8-Tetrachlorodibenzo[b,d]thiophene (CAS 134705-52-5)
- 1,2,6,9-Tetrachlorodibenzo[b,d]thiophene (CAS 134705-53-6)
- 1,2,8,9-Tetrachlorodibenzo[b,d]thiophene (CAS 134705-54-7)
Recommended Standards
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- Ethyl 1-(3-fluorophenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylate (CAS 346441-17-6)
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- (S)-2-Amino-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoic acid (CAS 878384-69-1)
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- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
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