Methyl (R)-2-amino-3-hydroxy-2-methylpropanoate hydrochloride CAS 134899-86-8
| CAS No. | 134899-86-8 |
| Molecular Formula | C5H11NO3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl (R)-2-amino-3-hydroxy-2-methylpropanoate hydrochloride.
Methyl (R)-2-amino-3-hydroxy-2-methylpropanoate hydrochloride (CAS 134899-86-8) is a high-purity analytical reference standard with the molecular formula C5H11NO3HCl and a molecular weight of 169.60 g/mol.
Based on its molecular formula C5H11NO3HCl, Methyl (R)-2-amino-3-hydroxy-2-methylpropanoate hydrochloride contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 169.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H11NO3 HCl |
| Molecular Weight | 169.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 4-Hydroxy-2-(trifluoromethoxy)benzonitrile (CAS 1261648-89-8)
- 3-(2,6-Dichlorophenyl)-3-hydroxypropanenitrile (CAS 868135-76-6)
- 2-[(2,6-Dichlorophenyl)methanesulfonyl]-4,5-diphenyl-1-propyl-1H-imidazole (CAS 339277-32-6)
- 6-Bromo-2-methylimidazo[1,2-b]pyridazine (CAS 1936575-36-8)
- 3'-Chloro-[1,1'-biphenyl]-4-sulfonyl chloride (CAS 478647-00-6)
- 2-Morpholino-N-phenethylethan-1-amine (CAS 312927-61-0)
- 2-Chloro-1-(1-(3,5-dichlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)ethan-1-one (CAS 757192-85-1)
- 1-(2,3-Dihydrobenzofuran-2-yl)-N,N-dimethylmethanamine (CAS 46192-79-4)
- Tantalum sulfide (CAS 12143-72-5)
- Cycloaspeptide A (CAS 109171-13-3)
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