Cytarabine Impurity 28 CAS 13491-47-9
| CAS No. | 13491-47-9 |
| Molecular Formula | C11H15N3O6 |
| Molecular Weight | 285.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Cytarabine Impurity 28 (CAS 13491-47-9) is a certified pharmaceutical impurity reference standard with the molecular formula C11H15N3O6 and a molecular weight of 285.25 g/mol.
The molecular framework of Cytarabine Impurity 28 (C11H15N3O6) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Cytarabine Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H15N3O6 |
| Molecular Weight | 285.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Nitrogen Atoms | 3 |
Related Cytarabine Standards
- Cytarabine Impurity 13 (CAS CATO-C4X-200513)
- Cytarabine Impurity 14 (CAS 3768-18-1)
- Cytarabine Impurity 29 (CAS CATO-C4X-200529)
- Cytarabine Impurity 30 (CAS CATO-C4X-200530)
- Cytarabine Impurity 33 (CAS CATO-C4X-200533)
- Cytarabine Impurity 34 (CAS CATO-C4X-200534)
- Cytarabine impurity 37 (CAS CATO-C4X-200537)
- Cytarabine Impurity 15 (CAS 60827-79-4)
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