5-(2,4-Dichlorophenyl)-1-methyl-1H-pyrazole-3-carboxylic acid CAS 1349449-91-7
| CAS No. | 1349449-91-7 |
| Molecular Formula | C11H8Cl2N2O2 |
| Molecular Weight | 271.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(2,4-Dichlorophenyl)-1-methyl-1H-pyrazole-3-carboxylic acid.
5-(2,4-Dichlorophenyl)-1-methyl-1H-pyrazole-3-carboxylic acid (CAS 1349449-91-7) is a high-purity analytical reference standard with the molecular formula C11H8Cl2N2O2 and a molecular weight of 271.10 g/mol.
5-(2,4-Dichlorophenyl)-1-methyl-1H-pyrazole-3-carboxylic acid (C11H8Cl2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(2,4-Dichlorophenyl)-1-methyl-1H-pyrazole-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8Cl2N2O2 |
| Molecular Weight | 271.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorophenyl Standards
- 1-(3,4-Dichlorophenyl)-5-methyl-1h-pyrazole-3-carboxylic acid (CAS 1020724-32-6)
- 1-[(3,4-dichlorophenyl)methyl]-1h-pyrazole-4-carboxylic acid (CAS 1035224-56-6)
- 5-(3,4-Dichlorophenyl)-1h-pyrazole-3-carbohydrazide (CAS 1046160-16-0)
- 2-(2,4-Dichlorophenyl)-N-(4h-1,2,4-triazol-3-yl)acetamide (CAS 1050774-60-1)
- 5-(2,4-Dichlorophenyl)-2-furohydrazide (CAS 1216144-12-5)
- 1-(2,4-dichlorophenyl)-5-methyl-1H-pyrazole-3-carboxylic acid (CAS 126067-48-9)
- 2-(4-(3,4-Dichlorophenyl)-1H-pyrazol-1-yl)acetic acid (CAS 1267250-16-7)
- 3-(2,4-Dichlorophenyl)-1-methyl-1H-pyrazole-5-carboxylic acid (CAS 133113-04-9)
Recommended Standards
- 1-(3,4-Dichlorobenzyl)-1H-imidazole-4-carboxylic acid (CAS 1369066-17-0)
- Ethyl 2,4-dichloro-1,5-naphthyridine-3-carboxylate (CAS 1312605-84-7)
- 1-Bromo-4-(methylsulfanyl)-2-(trifluoromethyl)benzene (CAS 1379356-82-7)
- 4-Chloro-1-[(2-chlorophenyl)methyl]-1H-pyrazole-3-carboxylic acid (CAS 1281872-55-6)
- 5-(4-Tert-butylphenyl)furan-2-carbaldehyde (CAS 343604-13-7)
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