5-Bromo-1-(4-fluorophenyl)pyridin-2(1h)-one CAS 1349798-33-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1349798-33-9
Molecular FormulaC11H7BrFNO
Molecular Weight268.08 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Bromo-1-(4-fluorophenyl)pyridin-2(1h)-one CAS 1349798-33-9 chemical structure

Description

The occurrence of 5-Bromo-1-(4-fluorophenyl)pyridin-2(1h)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 5-Bromo-1-(4-fluorophenyl)pyridin-2(1h)-one (CAS 1349798-33-9), a certified reference material (molecular formula C11H7BrFNO, MW 268.08 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, 5-Bromo-1-(4-fluorophenyl)pyridin-2(1h)-one is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 268.08 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H7BrFNO
Molecular Weight268.08 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF/Br-containing
Nitrogen Atoms1

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