5-(4-Chlorophenyl)-2-tosylpent-4-ynoic acid CAS 134993-74-1
| CAS No. | 134993-74-1 |
| Molecular Formula | C18H15ClO4S |
| Molecular Weight | 362.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-(4-Chlorophenyl)-2-tosylpent-4-ynoic acid (CAS 134993-74-1), molecular formula C18H15ClO4S and molecular weight 362.83 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(4-Chlorophenyl)-2-tosylpent-4-ynoic acid (C18H15ClO4S) is characterized by a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H15ClO4S |
| Molecular Weight | 362.83 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
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Recommended Standards
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