Naphthol AS-D CAS 135-61-5
| CAS No. | 135-61-5 |
| Molecular Formula | C18H15NO2 |
| Molecular Weight | 277.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Naphthol AS-D (C18H15NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Naphthol AS-D (CAS 135-61-5), molecular formula C18H15NO2 and molecular weight 277.32 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H15NO2 |
| Molecular Weight | 277.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Naphthol Standards
- 1,1＇-Bi-2-naphthol (CAS 602-09-5)
- Naphthol AS-CL Phosphate (CAS 18228-16-5)
- 2-Naphthol-6,8-Disulfonic Acid (CAS 118-32-1)
- 2-Naphthol-3,6-disulfonic acid (CAS 148-75-4)
- 1-Naphthol-4-sulfonic acid (CAS 84-87-7)
- 3-Phenyl-1-naphthol (CAS 30069-65-9)
- Naphthol AS-OL Acetate (CAS 7128-79-2)
- 3-Naphthol-2-carbonyl chloride (CAS 1734-00-5)
Recommended Standards
- 1-((Benzyloxy)carbonyl)azepane-2-carboxylic acid (CAS 1340252-54-1)
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- 2-(1-(((Benzyloxy)carbonyl)amino)cyclopentyl)acetic acid (CAS 1339747-03-3)
- tert-Butyl 3-(3-amino-4-cyano-1H-pyrazol-1-yl)-1-pyrrolidinecarboxylate (CAS 1353500-00-1)
- 2-(Allylcarbamothioyl)-N-(4-chlorophenyl)hydrazine-1-carboxamide (CAS 1024282-64-1)
- Biphenamine (CAS 3572-52-9)
- 2-[4-(tert-Butoxycarbonyl)-3,3-dimethyl-2-oxo-1-piperazinyl]acetic acid (CAS 1822800-93-0)
- Methyl 3-amino-2-benzylpropanoate hydrochloride (CAS 864182-43-4)
- tert-butyl ((1R,2R)-2-((3-fluorobenzyl)oxy)cyclohexyl)carbamate (CAS 2126143-16-4)
- 1-[(3-Bromophenyl)methyl]-2-methylpiperazine (CAS 1240573-44-7)
- tert-Butyldimethyl((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-1-yl)oxy)silane (CAS 2813233-17-7)
- 4-Chloro-N-isobutylquinazoline-7-carboxamide (CAS 1092460-43-9)
- (R)-Sulindac Methyl Ester (CAS 929081-61-8)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
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