4-Bromo-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid CAS 1350443-31-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1350443-31-0
Molecular FormulaC10H6BrFN2O2
Molecular Weight285.07 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Bromo-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid CAS 1350443-31-0 chemical structure

Description

CATO supplies 4-Bromo-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 1350443-31-0), a certified reference material (molecular formula C10H6BrFN2O2, MW 285.07 g/mol) for analytical method development and quality control.

4-Bromo-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (C10H6BrFN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-Bromo-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H6BrFN2O2
Molecular Weight285.07 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF/Br-containing
Nitrogen Atoms2

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