2-Bromo-4-chloro-1-ethynylbenzene CAS 1350535-10-2
| CAS No. | 1350535-10-2 |
| Molecular Formula | C8H4BrCl |
| Molecular Weight | 215.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 215.47 g/mol gives 2-Bromo-4-chloro-1-ethynylbenzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-Bromo-4-chloro-1-ethynylbenzene (CAS 1350535-10-2), a certified reference material (molecular formula C8H4BrCl, MW 215.47 g/mol) for analytical method development and quality control.
Based on its molecular formula C8H4BrCl, 2-Bromo-4-chloro-1-ethynylbenzene contains chlorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 215.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4BrCl |
| Molecular Weight | 215.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/Br-containing |
Related Bromo Standards
- 1-Bromo-4-chloro-2-ethynylbenzene (CAS 1268870-34-3)
- 4-Bromo-2-chloro-1-ethynylbenzene (CAS 1603573-36-9)
- 1-Bromo-3-chloro-5-ethynylbenzene (CAS 1639847-49-6)
- 4-Bromo-1-chloro-2-ethynylbenzene (CAS 1696309-52-0)
- 1-Bromo-3-chloro-2-ethynylbenzene (CAS 1856321-53-3)
- 1-Bromo-2-chloro-4-ethynylbenzene (CAS 313511-09-0)
- Methyl 2-bromo-4-chlorobutanoate (CAS 24666-02-2)
- 5-bromo-6-chloropyrazin-2-ol (CAS 913282-74-3)
Recommended Standards
- 2,2,2-Trichloro-1-(4,5-dihydrofuran-3-yl)ethanone (CAS 83124-80-5)
- 3-ethyl-5-(trichloromethyl)-1,2,4-oxadiazole (CAS 1196-99-2)
- 3-(Trimethylsilyl)propynylmagnesium bromide, 0.50 M in 2-MeTHF (CAS 78012-45-0)
- 3-Chloro-2-propoxypyridine-4-boronic acid (CAS 2096341-56-7)
- 2-chloro-5-(2-chlorophenyl)-1,3,4-thiadiazole (CAS 36894-93-6)
- 2-Ethylpropenoic acid (CAS 3586-58-1)
- Ethyl 4-(4-chlorobenzoyl)isoxazole-3-carboxylate (CAS 952182-77-3)
- (2-(5-(2-Methylcyclopropyl)furan-2-yl)cyclopropyl)methanamine (CAS 1343713-59-6)
- Samarium(III) phosphate hydrate (CAS 106534-67-2)
- N-(2,3-Difluorobenzyl)-1-(1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl)methanamine hydrochloride (CAS 1856073-78-3)
- 4-((3,5-Dichloropyridin-2-yl)oxy)aniline (CAS 67174-87-2)
- [2-(2-Benzyl-4-chlorophenoxy)ethyl]aminehydrochloride (CAS 1211474-07-5)
- (3S,5S)-3,5-Dimethylmorpholine (CAS 154634-96-5)
- Semaglutide impurity 64 (CAS CATO-C4X-222664)
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