4-Amino-3,5-difluorophenol CAS 135086-76-9
| CAS No. | 135086-76-9 |
| Molecular Formula | C6H5F2NO |
| Molecular Weight | 145.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Amino-3,5-difluorophenol (C6H5F2NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 4-Amino-3,5-difluorophenol (CAS 135086-76-9), a certified reference material (molecular formula C6H5F2NO, MW 145.11 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Amino-3,5-difluorophenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H5F2NO |
| Molecular Weight | 145.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- 3-Amino-2,6-difluorophenol (CAS 113512-69-9)
- 5-Amino-2,4-difluorophenol (CAS 113512-71-3)
- 6-Amino-2,3-difluorophenol (CAS 115551-33-2)
- 4-Amino-2,5-difluorophenol (CAS 120103-19-7)
- 4-Amino-2,6-difluorophenol (CAS 126058-97-7)
- 2-Amino-4,6-difluorophenol (CAS 133788-83-7)
- 2-Amino-3,6-difluorophenol (CAS 139548-98-4)
- 3-Amino-2,4-difluorophenol (CAS 1427330-97-9)
Recommended Standards
- 3,4-Difluoro-5-hydroxyaniline (CAS 1356339-34-8)
- methyl (4S)-2-oxooxazolidine-4-carboxylate (CAS 132682-22-5)
- 5-Oxomorpholine-3-carboxylic acid (CAS 1367717-62-1)
- 5-(Difluoromethyl)pyridin-3-ol (CAS 1393541-20-2)
- 4-Amino-2-(aminomethyl)pyridine (CAS 1000512-47-9)
- 1,4-Dichlorobutane-d8 (CAS 83547-96-0)
- N-([1,1'-biphenyl]-4-yl)-[1,1':3',1''-terphenyl]-4-amine (CAS 897671-66-8)
- 3-(2-Methylpyrrolidine-1-carbonyl)naphthalen-2-amine (CAS 1292432-64-4)
- Tricyclo[8.2.2.24,7]hexadeca-4,6,10,12,13,15-hexaene, 5,11-dibromo-, stereoisomer (CAS 196316-30-0)
- 2-Bromo-3-hydrazinylbenzonitrile (CAS 1256590-08-5)
- Z-Val-Ala-OMe (CAS 4817-92-9)
- Tert-butyl (1-((3-(4-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)piperidin-3-yl)carbamate (CAS 1781241-32-4)
- 2-Chloro-6-fluoro-3-methylbenzotrifluoridehydrochloride (CAS 1099597-61-1)
- 81988-89-8 UH11FDQ454 Ramoplanin A(sub 3) Ramoplanin A3 (S)-2-(3-Chloro-4-hydroxyphenyl)-N-(N(sup 2)-((2Z,4Z)-8-methyl-2,4-nonadienoyl)-(S)-asparaginyl-(2S,3S)-3-hydroxyasparaginyl-(R)-2-(p-hydroxyphenyl)glycyl-(R)-ornithyl-(2R,3R)-allothreonyl-2-(p-hydroxyphenyl)glycyl-2-(p-hydroxyphenyl)glycyl-(2S,3S)-allothreonyl-(S)-phenylalanyl-(R)-ornithyl-(S)-2-(p-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycyl-(2R,3R)-allothreonyl-(S)-2-(p-hydroxyphenyl)glycylglycyl-(S)-leucyl-(R)-alanyl)glycine psi1-lactone Ramoplanin A 1 (peptide moiety), 1-(N(sup 2)-methyl-1-oxo-2,4-nonadienyl)-L-asparagine)-11-(L-2-(4-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycine)-, (Z,Z)- UNII-UH11FDQ454 (CAS 81988-89-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com