3-fluoro-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carbaldehyde CAS 1351276-60-2
| CAS No. | 1351276-60-2 |
| Molecular Formula | C12H15BFNO3 |
| Molecular Weight | 251.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-fluoro-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carbaldehyde is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-fluoro-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carbaldehyde (CAS 1351276-60-2) is a high-purity analytical reference standard with the molecular formula C12H15BFNO3 and a molecular weight of 251.06 g/mol.
Structurally, 3-fluoro-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carbaldehyde (C12H15BFNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.5, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 251.06 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-fluoro-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carbaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15BFNO3 |
| Molecular Weight | 251.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related fluoro Standards
- 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carbaldehyde (CAS 1310384-06-5)
- 2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinaldehyde (CAS 1333319-63-3)
- 4-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinaldehyde (CAS 1352819-40-9)
- 5-Fluoro-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-4-carbaldehyde (CAS 1356930-47-6)
- 2-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isonicotinaldehyde (CAS 1356939-09-7)
- 3-fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carbaldehyde (CAS 1417200-18-0)
- (3-Fluoro-5-((4-oxopiperidin-1-yl)methyl)phenyl)boronic acid (CAS 1704063-68-2)
- (2-Fluoro-4-((4-oxopiperidin-1-yl)methyl)phenyl)boronic acid (CAS 1704064-22-1)
Recommended Standards
- Methyl 2,5-dichloro-3-hydroxy-6-methoxybenzoate (CAS 1327292-78-3)
- 5-Bromo-2-nitrothiophene-3-carbaldehyde oxime (CAS 1201924-03-9)
- 5-Bromo-2-nitrothiophene-3-carboxamide (CAS 1093878-20-6)
- 1-Bromo-1,1,2,2-tetrafluoroheptane (CAS 1445995-85-6)
- 2-(3-(Tert-butyl)-1H-pyrazol-1-yl)-1-(4-chlorophenyl)ethan-1-one (CAS 321538-45-8)
- Benzyl (4-chloro-2-fluorophenyl)carbamate (CAS 1820648-53-0)
- 1-Cyclopropyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid (CAS 677762-57-1)
- (2E)-1-(Furan-3-yl)-3-[3-(trifluoromethyl)phenyl]prop-2-en-1-one (CAS 478246-20-7)
- Phenyl 2-(diethoxyphosphoryl)acetate (CAS 3699-64-7)
- N-Ethyl-N-methyl-5-vinylpyridin-2-amine (CAS 1355195-85-5)
- 5-Cyclopropyl-1-methyl-1H-1,2,3-triazol-4-amine (CAS 1369433-20-4)
- Bis(p-heptyloxybenzylidene) p-phenylenediamine (CAS 24679-01-4)
- 4-(Methylsulfonyl)picolinic acid (CAS 1026676-25-4)
- Des-Pro31-Tirzepatide (CAS CATO-CPTD788943)
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