(2E)-3-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]prop-2-enoic acid CAS 1351395-65-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1351395-65-7
Molecular FormulaC8H14N2O3
Molecular Weight186.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2E)-3-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]prop-2-enoic acid CAS 1351395-65-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2E)-3-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]prop-2-enoic acid.

(2E)-3-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]prop-2-enoic acid (CAS 1351395-65-7) is a high-purity analytical reference standard with the molecular formula C8H14N2O3 and a molecular weight of 186.21 g/mol.

Based on its molecular formula C8H14N2O3, (2E)-3-[5-(propan-2-yl)-1,3,4-oxadiazol-2-yl]prop-2-enoic acid contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 186.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H14N2O3
Molecular Weight186.21 g/mol
AppearanceWhite to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1991
Nitrogen Atoms2

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