4-(Chloromethyl)-2-(trifluoromethyl)thiazole CAS 135207-07-7
| CAS No. | 135207-07-7 |
| Molecular Formula | C5H3ClF3NS |
| Molecular Weight | 201.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-(Chloromethyl)-2-(trifluoromethyl)thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-(Chloromethyl)-2-(trifluoromethyl)thiazole (CAS 135207-07-7), molecular formula C5H3ClF3NS and molecular weight 201.60 g/mol, is a CATO reference standard with documented purity and traceability.
4-(Chloromethyl)-2-(trifluoromethyl)thiazole (C5H3ClF3NS) contains a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H3ClF3NS |
| Molecular Weight | 201.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloromethyl Standards
- 2-(Chloromethyl)-4-trifluoromethyl-1,3-thiazole (CAS 1060815-98-6)
- 5-(Chloromethyl)-2-(trifluoromethyl)thiazole (CAS 131748-98-6)
- 1-(Chloromethyl)-2-methoxy-4-nitrobenzene (CAS 101080-01-7)
- 1-(Chloromethyl)-3-methoxy-5-nitrobenzene (CAS 1261854-28-7)
- α-Chloromethyl-4-nitrobenzenemethanol (CAS 13407-16-4)
- Methyl 4-(chloromethyl)-6-hydroxypicolinate (CAS 1393541-10-0)
- 1-(Chloromethyl)-2-methoxy-3-nitrobenzene (CAS 256455-93-3)
- 1-(Chloromethyl)-3-methoxy-2-nitrobenzene (CAS 53055-06-4)
Recommended Standards
- 4-Chloro-2-(difluoromethyl)-1H-indole (CAS 1375278-52-6)
- 2-(6-Chloro-2,4-difluoro-3-methylphenyl)acetonitrile (CAS 1858250-05-1)
- 2-Chloro-5-fluoro-7-methyl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one (CAS 1638771-04-6)
- 4-Amino-2-chloro-5-methoxybenzoic acid (CAS 1001347-19-8)
- Methyl 4-(4-oxobenzo[d][1,2,3]triazin-3(4H)-yl)butanoate (CAS 929972-09-8)
- 2-(3,3-Difluoropiperidin-1-yl)-4-nitrobenzaldehyde (CAS 1774900-09-2)
- 2-(3-Chlorophenyl)-4-[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-1,2-dihydrophthalazin-1-one (CAS 1291852-17-9)
- 1-(4-Methylphenyl)cyclopropanecarboxamide (CAS 681153-26-4)
- 2-(Difluoromethyl)-3-hydroxy-5-methoxypyridine-6-acetic acid (CAS 1805602-85-0)
- Ruthenium(II) 2,2,2-trifluoroacetate (CAS 61604-32-8)
- (4-Amino-2-methylphenyl)dimethylphosphine oxide (CAS 2361948-73-2)
- 6-(Difluoromethoxy)nicotinic Acid (CAS 1211535-62-4)
- 1-Ethyl-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline-6-carbaldehyde (CAS 80162-58-9)
- Semaglutide impurity 331 (CAS CATO-C4X-2226231)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com