1-(3-Chloro-5-fluorophenyl)-3-methylbutan-1-one CAS 1352209-75-6
| CAS No. | 1352209-75-6 |
| Molecular Formula | C11H12ClFO |
| Molecular Weight | 214.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3-Chloro-5-fluorophenyl)-3-methylbutan-1-one (CAS 1352209-75-6) is a high-purity analytical reference standard with the molecular formula C11H12ClFO and a molecular weight of 214.66 g/mol.
1-(3-Chloro-5-fluorophenyl)-3-methylbutan-1-one (C11H12ClFO) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12ClFO |
| Molecular Weight | 214.66 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 5-Chloro-1-(2-fluorophenyl)pentan-2-one (CAS 1056459-35-8)
- 1-(2-Chloro-6-fluorophenyl)pentan-2-one (CAS 1179741-86-6)
- 1-(2-Chloro-4-fluorophenyl)pentan-2-one (CAS 1247571-49-8)
- 1-(3-Chloro-4-fluorophenyl)-3-methylbutan-1-one (CAS 1268052-38-5)
- 1-(3-Chloro-4-fluorophenyl)pentan-1-one (CAS 1339657-45-2)
- 1-(3-Chloro-2-fluorophenyl)pentan-1-one (CAS 1343048-33-8)
- 1-(4-Chloro-2-fluorophenyl)pentan-1-one (CAS 1343879-99-1)
- 1-(4-Chloro-3-fluorophenyl)-3-methylbutan-1-one (CAS 1352208-38-8)
Recommended Standards
- 1-(3-Chloro-5-fluorophenyl)pentan-1-one (CAS 1352208-92-4)
- 1-(4-Chloro-3-fluorophenyl)pentan-1-one (CAS 1352224-73-7)
- 1-(3-Chloro-5-fluorophenyl)-1-cyclopropylethan-1-ol (CAS 1379357-86-4)
- (1-(2-Chloro-6-fluorobenzyl)cyclopropyl)methanol (CAS 1486039-02-4)
- 1-[(1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-yl]ethanone hydrochloride (CAS 1190927-48-0)
- 4,5-Dibromopyrimidine-2-carbonitrile (CAS 1807235-33-1)
- 4-(Pentyloxy)benzenesulfonamide (CAS 1141-94-2)
- 6-Bromo-5',5'-dimethyl-4',5'-dihydro-2'H-spiro[benzo[b][1,4]oxazine-2,3'-furan]-3(4H)-one (CAS 2658493-88-8)
- Methyl (2S)-2-(2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoate (CAS 1033882-29-9)
- N-(2,4-dichlorophenyl)-2-((4-methoxyphenyl)sulfonyl)acetamide (CAS 339108-04-2)
- Anthracen-1-ol (CAS 71036-28-7)
- methyl 3-hydrazinyl-2-methylbenzoate hydrochloride (CAS 1955540-35-8)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(acetamidothio)-3-methylbutanoic acid (CAS 1246647-73-3)
- D-Val23-Tirzepatide (CAS CATO-CPTD788911)
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