1-(3-Chloro-4-methylphenyl)-2,2-difluoroethan-1-one CAS 1352222-18-4
| CAS No. | 1352222-18-4 |
| Molecular Formula | C9H7ClF2O |
| Molecular Weight | 204.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 204.60 g/mol gives 1-(3-Chloro-4-methylphenyl)-2,2-difluoroethan-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(3-Chloro-4-methylphenyl)-2,2-difluoroethan-1-one (CAS 1352222-18-4), molecular formula C9H7ClF2O and molecular weight 204.60 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(3-Chloro-4-methylphenyl)-2,2-difluoroethan-1-one (C9H7ClF2O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(3-Chloro-4-methylphenyl)-2,2-difluoroethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H7ClF2O |
| Molecular Weight | 204.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-1-(2,5-difluorophenyl)propan-1-one (CAS 1016527-64-2)
- 3-(4-Chloro-3,5-difluorophenyl)propanal (CAS 1036396-38-9)
- 3-Chloro-1-(3,4-difluorophenyl)-1-propanone (CAS 1215969-79-1)
- 1-Chloro-3-(3,4-difluorophenyl)propan-2-one (CAS 1221342-53-5)
- 1-Chloro-3-(3,5-difluorophenyl)propan-2-one (CAS 1221343-06-1)
- 4-Chloro-6,6-difluoro-5,6,7,8-tetrahydroquinazoline (CAS 1256955-43-7)
- 3-(3-Chloro-4,5-difluorophenyl)propanal (CAS 1260829-42-2)
- 1-(2-Chloro-3,6-difluorophenyl)propan-2-one (CAS 1305323-90-3)
Recommended Standards
- 1-(5-Chloro-2-methylphenyl)-2,2-difluoroethan-1-one (CAS 1352216-28-4)
- 1-(4-Chloro-3-methylphenyl)-2,2-difluoroethan-1-one (CAS 1352232-00-8)
- 1-(3-Chloro-2-methylphenyl)-2,2-difluoroethan-1-one (CAS 1352215-89-4)
- 2-Chloro-1-(2,5-difluoro-4-methylphenyl)ethan-1-one (CAS 1379327-18-0)
- 3-((1,1,1-Trifluoropropan-2-yl)oxy)azetidine (CAS 1502257-94-4)
- 4-Cyano-2-(trifluoromethyl)benzamide (CAS 1203956-49-3)
- (R,E)-N-((1S,5S,6R)-5-Hydroxy-5-((1E,3E,5E)-7-((2-hydroxy-5-oxocyclopent-1-en-1-yl)amino)-7-oxohepta-1,3,5-trien-1-yl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)-2,4-dimethyloct-2-enamide (CAS 139023-58-8)
- N-(5-Amino-2,4-dichlorophenyl)-4-methylbenzenesulfonamide (CAS 1119390-49-6)
- rac-(2R,3S)-2-(3-methyl-1,2,4-oxadiazol-5-yl)oxolan-3-amine hydrochloride (CAS 2044705-76-0)
- GK187 (CAS 1071001-50-7)
- zinc arsenide (CAS 12006-40-5)
- Tridecafluorohexane-1-Sulfonic Acid Potassium Salt (CAS 3871-99-6)
- Phentolamine Mesilate EP Impurity A (CAS 2724727-52-8（free base）)
- Stresscopin-Related Peptide (human) (CAS 348626-74-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com