1-(4-(Tert-butyl)phenyl)-2-chloro-2,2-difluoroethan-1-one CAS 1352222-75-3

Description

The occurrence of 1-(4-(Tert-butyl)phenyl)-2-chloro-2,2-difluoroethan-1-one is closely related to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-(4-(Tert-butyl)phenyl)-2-chloro-2,2-difluoroethan-1-one (CAS 1352222-75-3) is a high-purity analytical reference standard with the molecular formula C12H13ClF2O and a molecular weight of 246.68 g/mol.

The molecular framework of 1-(4-(Tert-butyl)phenyl)-2-chloro-2,2-difluoroethan-1-one (C12H13ClF2O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 1-(4-(Tert-butyl)phenyl)-2-chloro-2,2-difluoroethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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