2-Chloro-1-(2,3-dimethylphenyl)-2,2-difluoroethan-1-one CAS 1352224-82-8
| CAS No. | 1352224-82-8 |
| Molecular Formula | C10H9ClF2O |
| Molecular Weight | 218.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-1-(2,3-dimethylphenyl)-2,2-difluoroethan-1-one (C10H9ClF2O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-Chloro-1-(2,3-dimethylphenyl)-2,2-difluoroethan-1-one (CAS 1352224-82-8) is a high-purity analytical reference standard with the molecular formula C10H9ClF2O and a molecular weight of 218.63 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-1-(2,3-dimethylphenyl)-2,2-difluoroethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9ClF2O |
| Molecular Weight | 218.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-Chloro-1-(2,5-difluorophenyl)butan-1-one (CAS 1216260-42-2)
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- 2-Chloro-1-(4-ethylphenyl)-2,2-difluoroethan-1-one (CAS 1352218-43-9)
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