1-(3-Chloro-4-methylphenyl)-2,2,3,3,3-pentafluoropropan-1-one CAS 1352224-93-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1352224-93-1
Molecular FormulaC10H6ClF5O
Molecular Weight272.60 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(3-Chloro-4-methylphenyl)-2,2,3,3,3-pentafluoropropan-1-one CAS 1352224-93-1 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(3-Chloro-4-methylphenyl)-2,2,3,3,3-pentafluoropropan-1-one.

CATO supplies 1-(3-Chloro-4-methylphenyl)-2,2,3,3,3-pentafluoropropan-1-one (CAS 1352224-93-1), a certified reference material (molecular formula C10H6ClF5O, MW 272.60 g/mol) for analytical method development and quality control.

The molecular framework of 1-(3-Chloro-4-methylphenyl)-2,2,3,3,3-pentafluoropropan-1-one (C10H6ClF5O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 1-(3-Chloro-4-methylphenyl)-2,2,3,3,3-pentafluoropropan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H6ClF5O
Molecular Weight272.60 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF/Cl-containing

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